Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.72 |
| ▸ | SCD | O00767 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13464505 | 0.93 | LPAR1 (0.75) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809589 | 0.91 | LPAR1 (0.83) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809806 | 0.90 | LPAR1 (0.70) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809804 | 0.90 | LPAR1 (0.70) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809802 | 0.90 | LPAR1 (0.70) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809782 | 0.88 | LPAR1 (0.68) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809781 | 0.88 | LPAR1 (0.68) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1809779 | 0.88 | LPAR1 (0.68) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL1812311 | 0.85 | LPAR1 (0.88) | LPAR1SCDF10HTR2CSLC6A4 | |
| SCHEMBL13464470 | 0.83 | LPAR1 (0.67) | LPAR1SCDGPR132NOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264790-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI (FR) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264790-A1 | ACYLAMINO-SUBSTITUTED CYCLIC CARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | LPAR2, LIPG, EDF1 | LPAR1 4/4885SCD 1567/4885F10 112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.