⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4267614 | 0.69 | — | — | |
| SCHEMBL21764173 | 0.64 | — | — | |
| SCHEMBL7853864 | 0.60 | — | — | |
| SCHEMBL28224579 | 0.60 | — | — | |
| SCHEMBL19113231 | 0.58 | — | — | |
| SCHEMBL14944293 | 0.57 | — | — | |
| SCHEMBL31265569 | 0.56 | — | — | |
| SCHEMBL28077581 | 0.56 | — | — | |
| SCHEMBL24756242 | 0.55 | — | — | |
| SCHEMBL14019548 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9604900-B2 | Inhibitors of viral replication, their process of preparation and their therapeutical uses | LABORATOIRE BIODIM (FR) | 2017-03-28 | — | — | US | disclosed |
| US-9604900-B2 | Inhibitors of viral replication, their process of preparation and their therapeutical uses | LABORATOIRE BIODIM (FR) | 2017-03-28 | — | — | US | disclosed |
| CN-101889009-B | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA N.V. (BE) | 2014-10-29 | — | — | CN | disclosed |
| US-20140031338-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2014-01-30 | — | — | US | disclosed |
| US-20140031338-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2014-01-30 | — | — | US | disclosed |
| WO-2012140243-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2012-10-18 | — | — | WO | disclosed |
| CN-101889009-A | The c-fms kinase inhibitor | JANSSEN PHARMACEUTICA NV | 2010-11-17 | — | — | CN | disclosed |
| CN-101472914-A | C-FMS kinase inhibitors | JANSSEN PHARMACEUTICA NV (BE) | 2009-07-01 | — | — | CN | disclosed |
| CN-101466686-A | C-FMS kinase inhibitor | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-24 | — | — | CN | disclosed |