⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31265569 | 0.93 | — | — | |
| SCHEMBL27966118 | 0.88 | — | — | |
| SCHEMBL28224579 | 0.84 | — | — | |
| SCHEMBL7351338 | 0.65 | — | — | |
| SCHEMBL107504 | 0.65 | — | — | |
| SCHEMBL7346799 | 0.65 | — | — | |
| SCHEMBL595872 | 0.64 | ALDH1A1 (0.44) | — | |
| SCHEMBL3675016 | 0.62 | — | — | |
| SCHEMBL18137233 | 0.62 | — | — | |
| Cyclohexene SCHEMBL8175251 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022117473-A1 | HETEROCYCLIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-09 | — | — | WO | disclosed |
| CN-103012390-B | As the indole derivatives of S1P1 receptor stimulant | GLAXO GROUP LTD. (GB) | 2015-08-26 | — | — | CN | disclosed |
| CN-103492376-B | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LTD | 2015-07-22 | — | — | CN | disclosed |
| CN-104334525-A | Catechol o-methyltransferase activity inhibiting compounds | ORION CORP | 2015-02-04 | — | — | CN | disclosed |
| CN-101889009-B | Inhibitors of c-fms kinase | JANSSEN PHARMACEUTICA N.V. (BE) | 2014-10-29 | — | — | CN | disclosed |
| CN-103492376-A | Bicyclic heterocycle compounds and their uses in therapy | ASTEX THERAPEUTICS LTD | 2014-01-01 | — | — | CN | disclosed |
| EP-2592671-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC EL DISPLAY DEVICE, AND ORGANIC EL LIGHTING | Mitsubishi Chemical Corporation (JP) | 2013-05-15 | — | — | EP | disclosed |
| CN-101663297-B | Oxadiazole substituted indazole derivatives for use as sphingosine 1-phosphate (s1p) agonists | GLAXO GROUP LTD | 2013-05-08 | — | — | CN | disclosed |
| CN-101952283-B | Imidazo [1,2-a ] pyridine and imidazo [1,2-b ] pyridazine derivatives | HOFFMANN LA ROCHE | 2013-04-17 | — | — | CN | disclosed |
| CN-103012390-A | Indole derivatives as S1P1 receptor | GLAXO GROUP LTD | 2013-04-03 | — | — | CN | disclosed |
| CN-101611033-B | Indole derivatives as S1P1 receptor agonists | GLAXO GROUP LTD | 2012-10-31 | — | — | CN | disclosed |
| CN-102652128-A | 4-Oxo-1H-quinoline-3-carboxamides as modulators of ATP-binding cassette transporters | VERTEX PHARMA | 2012-08-29 | — | — | CN | disclosed |
| CN-101437514-B | Inhibitors of C-FMS kinase | JANSSEN PHARMACEUTICA NV | 2012-04-25 | — | — | CN | disclosed |
| CN-101374835-B | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | TRANSTECH PHARMA INC | 2012-04-25 | — | — | CN | disclosed |
| CN-101952283-A | Novel imidazo [1,2-a ] pyridine and imidazo [1,2-b ] pyridazine derivatives | HOFFMANN LA ROCHE | 2011-01-19 | — | — | CN | disclosed |
| CN-101889009-A | The c-fms kinase inhibitor | JANSSEN PHARMACEUTICA NV | 2010-11-17 | — | — | CN | disclosed |
| CN-101663297-A | Oxadiazole substituted indazole derivatives for use as sphingosine 1-phosphate (s1p) agonists | GLAXO GROUP LTD | 2010-03-03 | — | — | CN | disclosed |
| CN-101611033-A | Indole derivatives as S1P1 receptor agonists | GLAXO GROUP LTD (GB) | 2009-12-23 | — | — | CN | disclosed |
| CN-101466686-A | C-FMS kinase inhibitor | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-24 | — | — | CN | disclosed |
| CN-101374835-A | Substituted imidazole derivatives, compositions, and methods of use as PTPase inhibitors | TRANSTECH PHARMA INC (US) | 2009-02-25 | — | — | CN | disclosed |