Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.40 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29812158 | 0.89 | PTGS1 (0.46) | PTGS1PTGS2KMT2AMEN1PLA2G1B | |
| SCHEMBL13278421 | 0.85 | KMT2A (0.37) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL1345452 | 0.79 | CYP2C19 (0.49) | PTGS1PTGS2KMT2AHTTMT-CO2 | |
| SCHEMBL31383801 | 0.79 | CYP2C19 (0.49) | PTGS1PTGS2KMT2AHTTMT-CO2 | |
| SCHEMBL13281321 | 0.79 | POLB (0.34) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL13465478 | 0.77 | POLB (0.36) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL31455895 | 0.77 | PTGS1 (0.40) | PTGS1PTGS2KMT2AMEN1HTT | |
| SCHEMBL27964846 | 0.77 | KMT2A (0.41) | PTGS1PTGS2KMT2AMEN1PLA2G1B | |
| SCHEMBL27550566 | 0.76 | KMT2A (0.44) | PTGS1PTGS2KMT2AMEN1PLA2G1B | |
| SCHEMBL6017451 | 0.74 | KMT2A (0.47) | PTGS1PTGS2KMT2AMEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012140243-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2012-10-18 | — | — | WO | disclosed |