Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13465400 | 0.81 | MAPK1 (0.36) | POLBKMT2AMEN1PLA2G1BHTT | |
| SCHEMBL13465755 | 0.78 | CYP2C19 (0.43) | POLBRECQLKMT2AMEN1HTT | |
| SCHEMBL13465472 | 0.77 | PTGS1 (0.42) | POLBRECQLKMT2AMEN1PLA2G1B | |
| SCHEMBL13278421 | 0.76 | KMT2A (0.37) | POLBRECQLKMT2AMEN1PLA2G1B | |
| SCHEMBL13281321 | 0.76 | POLB (0.34) | POLBRECQLKMT2AMEN1PLA2G1B | |
| SCHEMBL28979022 | 0.71 | KMT2A (0.55) | KMT2AMEN1SLC6A4ESR1ESR2 | |
| SCHEMBL27964846 | 0.69 | KMT2A (0.41) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL2848191 | 0.69 | ESR1 (0.43) | KMT2AMEN1ADRB2ADRB1ADRB3 | |
| SCHEMBL27550566 | 0.68 | KMT2A (0.44) | KMT2AMEN1PLA2G1BHTTNPSR1 | |
| SCHEMBL13465551 | 0.68 | ESR1 (0.32) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012140243-A1 | INHIBITORS OF VIRAL REPLICATION, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTICAL USES | LABORATOIRE BIODIM (FR) | 2012-10-18 | — | — | WO | disclosed |