Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9451204 | 1.00 | — | — | |
| SCHEMBL16560498 | 1.00 | TSHR (0.56) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL3055663 | 1.00 | TSHR (0.56) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL10397317 | 1.00 | TSHR (0.56) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL11867093 | 1.00 | TSHR (0.56) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL7634467 | 0.97 | — | — | |
| SCHEMBL6537074 | 0.88 | — | — | |
| SCHEMBL20854579 | 0.82 | CES2 (0.52) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL20854578 | 0.82 | CES2 (0.52) | TSHRALDH1A1GPR84PPARGPPARD | |
| SCHEMBL20854580 | 0.82 | CES2 (0.52) | TSHRALDH1A1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170952-A9 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2013-02-21 | — | — | WO | disclosed |
| WO-2012170952-A2 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2012-12-13 | — | — | WO | disclosed |
| WO-2012141783-A1 | OLEFINS AND METHODS FOR MAKING THE SAME | Amyris, Inc. (US) | 2012-10-18 | — | — | WO | disclosed |
| WO-2012141784-A1 | BASE OILS AND METHODS FOR MAKING THE SAME | Amyris, Inc. (US) | 2012-10-18 | — | — | WO | disclosed |