Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805817 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL888494 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL888492 | 0.82 | SMN1; SMN2 (0.64) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL31633995 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL31633994 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL13265213 | 0.79 | ALDH1A1 (0.46) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10463854 | 0.78 | ALDH1A1 (0.44) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL7981851 | 0.75 | CHRNA1 (0.64) | ALDH1A1LMNARECQLKMT2ASMN1; SMN2 | |
| SCHEMBL2755018 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNARECQLKMT2AGAA | |
| SCHEMBL5833192 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNARECQLKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511279-A1 | DIVALENT AND OXABRIDGED HETEROCYCLIC NEONICOTINOID COMPOUNDS AND PREPARATION METHODS THEREOF | East China University of Science and Technology (CN) | 2012-10-17 | — | — | EP | disclosed |