Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PNMT | P11086 | 4/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12689997 | 1.00 | ALDH1A1 (0.38) | ALDH1A1HIF1ABACE2BACE1RAB9A | |
| SCHEMBL12690008 | 0.81 | BACE2 (0.41) | ALDH1A1HIF1ABACE2BACE1RAB9A | |
| SCHEMBL12690193 | 0.79 | BACE1 (0.40) | BACE2BACE1 | |
| SCHEMBL932759 | 0.79 | BACE1 (0.35) | BACE2BACE1 | |
| SCHEMBL6877967 | 0.79 | BACE1 (0.35) | BACE2BACE1 | |
| SCHEMBL12690183 | 0.79 | BACE1 (0.32) | BACE1 | |
| SCHEMBL18195491 | 0.79 | BACE1 (0.35) | BACE2BACE1 | |
| SCHEMBL12690003 | 0.75 | BACE1 (0.35) | BACE2BACE1 | |
| SCHEMBL17307754 | 0.73 | BACE2 (0.40) | ALDH1A1HIF1ABACE2BACE1 | |
| SCHEMBL17307748 | 0.73 | BACE2 (0.40) | ALDH1A1HIF1ABACE2BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511269-A1 | FUSED HETEROCYCLIC COMPOUND HAVING AMINO GROUP | Shionogi & Co., Ltd. (JP) | 2012-10-17 | — | — | EP | disclosed |