Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13467484 | 0.89 | PRKAG1 (0.53) | PAX8PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL14713461 | 0.85 | PRKAG1 (0.55) | PAX8PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL12579672 | 0.85 | PRKAG1 (0.55) | PAX8PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL20626486 | 0.85 | PRKAG1 (0.55) | PAX8PRKAG1PRKAA1PRKAB1 | |
| SCHEMBL13467459 | 0.82 | ABL1 (0.56) | PRKAG1PRKAA1PRKAB1ALDH1A1LMNA | |
| SCHEMBL20626294 | 0.82 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL14714052 | 0.82 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL20626293 | 0.82 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL14713327 | 0.82 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL27881273 | 0.82 | PRKAG1 (0.75) | PRKAG1PRKAA1PRKAB1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2511283-A1 | N6-SUBSTITUTED ADENOSINE DERIVATIVES, N6-SUBSTITUTED ADENINE DERIVATIVES AND USES THEREOF | INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES (CN) | 2012-10-17 | — | — | EP | disclosed |