Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18156669 | 0.92 | AHR (0.44) | AHRPGRMAOAPDK2CYP1A2 | |
| SCHEMBL18156668 | 0.90 | PGR (0.43) | AHRPGRMAOAPDK2CYP1A2 | |
| SCHEMBL13467921 | 0.85 | AHR (0.51) | AHRPGRMAOACYP1A2MAPT | |
| SCHEMBL19011152 | 0.83 | PGR (0.46) | AHRPGRMAOAPDK2CYP1A2 | |
| SCHEMBL13467893 | 0.83 | AHR (0.41) | AHRPGRMAOACYP1A2MAPT | |
| SCHEMBL17523465 | 0.83 | PDK2 (0.41) | AHRPGRMAOAPDK2CYP1A2 | |
| SCHEMBL21742673 | 0.83 | PDK2 (0.41) | AHRPGRMAOAPDK2MAPT | |
| SCHEMBL9917128 | 0.83 | PDK2 (0.41) | AHRPGRMAOAPDK2MAPT | |
| SCHEMBL18731701 | 0.82 | AHR (0.51) | AHRPGRMAOACYP1A2MAPT | |
| SCHEMBL23184663 | 0.82 | AHR (0.45) | AHRPGRMAOACYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140027757-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-01-30 | — | — | US | disclosed |
| US-20140027757-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2014-01-30 | — | — | US | disclosed |
| WO-2012141229-A1 | NOVEL SPIRO COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE HAVING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-10-18 | — | — | WO | disclosed |