SCHEMBL13469342

SCHEMBL13469342

CCOC(=O)CCNC(=O)c1ccccc1CC

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HCRTR1 O43613 2/20 0.50
CYP4F2 P78329 2/20 0.50
CYP4A11 Q02928 2/20 0.50
HDAC3 O15379 1/20 0.48
HDAC1 Q13547 1/20 0.48
TSHR P16473 2/20 0.47
HTT P42858 2/20 0.47
TOP2A P11388 1/20 0.46
ALDH1A1 P00352 1/20 0.46
PRSS1 P07477 1/20 0.45
CTSG P08311 1/20 0.45
CTRB1 P17538 1/20 0.45
CMA1 P23946 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.44
HPGD P15428 2/20 0.44
NPSR1 Q6W5P4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13468193 0.87 CHRM1 (0.55) HCRTR1TSHRHTTALDH1A1SMN1; SMN2
SCHEMBL15528646 0.83 HCRTR1 (0.76) HCRTR1HDAC3HDAC1TSHRALDH1A1
SCHEMBL7325137 0.83 CRBN (0.51) HCRTR1TSHRHTTTOP2AALDH1A1
SCHEMBL15614413 0.83 HCRTR1 (0.51) HCRTR1TSHRHTTTOP2AALDH1A1
SCHEMBL27375291 0.82 CHRNB2 (0.54) HCRTR1HDAC3HDAC1HTTNPSR1
SCHEMBL3209406 0.81 NPSR1 (0.58) HCRTR1HDAC3HDAC1TSHRHTT
SCHEMBL27439930 0.80 PRSS1 (0.71) TOP2AALDH1A1PRSS1CTSGCTRB1
SCHEMBL13962647 0.78 CYP4F2 (0.55) CYP4F2CYP4A11TSHRALDH1A1SMN1; SMN2
SCHEMBL13162369 0.78 HPGD (0.59) HCRTR1HDAC3TSHRHTTALDH1A1
SCHEMBL22515531 0.78 HTT (0.56) HCRTR1HDAC3HDAC1TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012139891-A1 SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-10-18 WO disclosed