SCHEMBL13469397

SCHEMBL13469397

CCOC(=O)c1cc(OC)c(OC)cc1CC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.53
GAA P10253 4/20 0.51
ALDH1A1 P00352 2/20 0.51
DPP4 P27487 4/20 0.50
LMNA P02545 3/20 0.50
MAPT P10636 2/20 0.50
HSD17B2 P37059 1/20 0.49
TSHR P16473 1/20 0.48
KCNK3 O14649 1/20 0.47
HMGCR P04035 1/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13469249 0.88 HSD17B2 (0.56) GAAALDH1A1DPP4LMNAMAPT
SCHEMBL8589287 0.88 KMT2A (0.49) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL11377134 0.87 DPP4 (0.50) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL30575737 0.87 DPP4 (0.50) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL13469255 0.85 KDM4E (0.59) KMT2AGAAALDH1A1LMNAMAPT
SCHEMBL2900687 0.85 KMT2A (0.65) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL13468491 0.84 KMT2A (0.54) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL5240208 0.82 LCK (0.53) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL31609504 0.81 DPP4 (0.45) KMT2AGAAALDH1A1DPP4LMNA
SCHEMBL3373962 0.81 KDM4E (0.69) KMT2AGAAALDH1A1DPP4LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016008862-A1 SUBSTITUTED VINYL AND ALKYNYL CYANOCYCLOALKANOLS AND VINYL AND ALKYNYL CYANOHETEROCYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2016-01-21 WO disclosed
WO-2012139891-A1 SUBSTITUTED VINYL AND ALKINYL CYCLOHEXENOLS AS ACTIVE AGENTS AGAINST ABIOTIC STRESS IN PLANTS BAYER CROPSCIENCE AG (DE) 2012-10-18 WO disclosed