Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | DPP4 | P27487 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788470 | 0.93 | KMT2A (0.57) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL31463978 | 0.89 | KMT2A (0.54) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL6859316 | 0.89 | KMT2A (0.54) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL1964834 | 0.87 | HTR4 (0.53) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL20060067 | 0.87 | KMT2A (0.56) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL6584127 | 0.87 | HTR4 (0.53) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL27455432 | 0.87 | HSD17B2 (0.59) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL13468491 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL3615833 | 0.86 | KMT2A (0.54) | KMT2AALDH1A1GAATSHRHSD17B2 | |
| SCHEMBL11310863 | 0.85 | KMT2A (0.50) | KMT2AALDH1A1GAATSHRHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015168368-A1 | FLUOROALKYLATION REAGENTS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2015-11-05 | — | — | WO | disclosed |
| CN-102249901-A | Preparation method of 2, 5-dialkoxy terephthalic acid | SHANDONG NON METALLIC MATERIAL RES INST | 2011-11-23 | — | — | CN | disclosed |
| US-20100297588-A1 | DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-11-25 | — | — | US | disclosed |
| EP-2214621-A2 | DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS | 3M Innovative Properties Company (US) | 2010-08-11 | — | — | EP | disclosed |
| WO-2009058854-A2 | DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2009-05-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100297588-A1 | DENTAL COMPOSITIONS WITH NATURAL TOOTH FLUORESCENCE AND METHODS | PITHD1, DDX24, DACH1 | KMT2A 1428/4885ALDH1A1 3070/4885GAA 2121/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.