Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.37 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.31 |
| ▸ | ALB | P02768 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.31 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384630 | 0.83 | FGFR1 (0.39) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL16513183 | 0.82 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL15482195 | 0.82 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL22820554 | 0.81 | FGFR1 (0.39) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL15576948 | 0.81 | FGFR1 (0.39) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL13468606 | 0.80 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL24420596 | 0.79 | FGFR1 (0.43) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL13468599 | 0.79 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL18661627 | 0.79 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 | |
| SCHEMBL13758938 | 0.79 | FGFR1 (0.37) | FGFR1PDE3APDE4DSLC29A1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012142093-A2 | 2'-CYANO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2012-10-18 | — | — | WO | disclosed |