⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30337581 | 1.00 | — | — | |
| SCHEMBL5347385 | 0.97 | ACHE (0.40) | — | |
| SCHEMBL47042 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL27656812 | 0.77 | HDAC1 (0.44) | — | |
| Fluoride SCHEMBL27726514 | 0.77 | HDAC1 (0.44) | — | |
| SCHEMBL17784486 | 0.77 | HDAC1 (0.44) | — | |
| SCHEMBL8146926 | 0.75 | CYP2A6 (0.46) | — | |
| SCHEMBL26750806 | 0.75 | CYP2A6 (0.46) | — | |
| SCHEMBL40336 | 0.75 | — | — | |
| SCHEMBL29388695 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 733 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110078633-B | Preparation method of 4-fluoro-3-methoxy-5-methylaniline hydrochloride | 爱斯特（成都）生物制药股份有限公司 | 2021-05-11 | — | — | CN | claimed |
| WO-2020237806-A1 | PREPARATION METHOD FOR 4-FLUORINE-3-METHOXYL-5-METHYLANILINE HYDROCHLORIDE | 爱斯特（成都）生物制药股份有限公司 | 2020-12-03 | — | — | WO | claimed |
| EP-0068038-A1 | (+)-(4R,6S)-(E)-6-(2-(4'-fluoro-3,3',5-trimethyl-(1,1'-biphenyl)-2-yl)ethenyl)-3,4,5,6-tetrahydro-4-hydroxy-2H-pyran-2-one, a process for preparing and a pharmaceutical composition containing the same | MERCK & CO. INC. (US) | 1983-01-05 | — | — | EP | claimed |
| US-20260078117-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS INC (US) | 2026-03-19 | — | — | US | disclosed |
| EP-3897833-B1 | INHIBITORS OF APOL1 AND METHODS OF USING SAME | VERTEX PHARMA (US) | 2026-02-04 | — | — | EP | disclosed |
| US-12459958-B2 | Tricyclic compounds as HPK1 inhibitor and the use thereof | BEONE MEDICINES I GMBH (CH) | 2025-11-04 | — | — | US | disclosed |
| US-20250326770-A1 | BENZOTRIAZOLE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-10-23 | — | — | US | disclosed |
| US-20250296939-A1 | BENZOTHIOPHENE COMPOUND | KYOTO PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2025-09-25 | — | — | US | disclosed |
| US-20250282724-A1 | BENZOTRIAZOLE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-09-11 | — | — | US | disclosed |
| US-12378260-B2 | Benzotriazole compound | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2025-08-05 | — | — | US | disclosed |
| WO-2025119206-A1 | GLP-1 RECEPTOR TARGETING COMPOUNDS AND USES THEREOF | FORTVITA BIOLOGICS INC. (KY) | 2025-06-12 | — | — | WO | disclosed |
| US-4855321-A | Antihypercholesterolemic compounds | MERCK & CO., INC. (US) | 1989-08-08 | — | — | US | disclosed |
| WO-1989005639-A1 | NOVEL HMG-CoA REDUCTASE INHIBITORS | RORER INTERNATIONAL (OVERSEAS) INC. (US) | 1989-06-29 | — | — | WO | disclosed |
| CN-1030761-A | Phosphorated 3-hydroxyl-3-first glutaryl CoA-reductase inhibitors, new intermediate and method | SQUIBB & SONS INC (US) | 1989-02-01 | — | — | CN | disclosed |
| CN-88103091-A | Phosphorous HMG-COA reductase inhibitor, new intermediate and using method | SQUIBB & SONS INC (US) | 1988-12-21 | — | — | CN | disclosed |
| US-4772626-A | ENZYME INHIBITORS, ANTILIPEMIC AGENTS, TETRAHYDRO-HYDROXYPYRANONES | MERCK & CO., INC. (US) | 1988-09-20 | — | — | US | disclosed |
| EP-0232997-A1 | Antihypercholesterolemic compounds | MERCK & CO. INC. (US) | 1987-08-19 | — | — | EP | disclosed |
| US-4620025-A | NICKEL COMPLEX CATALYSTS | MERCK & CO., INC. (US) | 1986-10-28 | — | — | US | disclosed |
| EP-0068038-B1 | (+)-(4R,6S)-(E)-6-(2-(4'-FLUORO-3,3',5-TRIMETHYL-(1,1'-BIPHENYL)-2-YL)ETHENYL)-3,4,5,6-TETRAHYDRO-4-HYDROXY-2H-PYRAN-2-ONE, A PROCESS FOR PREPARING AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | MERCK & CO. INC. (US) | 1985-09-25 | — | — | EP | disclosed |
| US-3947460-A | SEDATIVES-HYPNOTIC, TRANQUILIZER | SANDOZ, INC. (US) | 1976-03-30 | — | — | US | disclosed |