Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 10/20 | 0.38 |
| ▸ | PANK3 | Q9H999 | 3/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860558 | 0.85 | KDM4E (0.39) | FASNCHEK1PANK3 | |
| SCHEMBL12686799 | 0.84 | FASN (0.39) | FASNCHEK1PANK3HRH2HRH1 | |
| SCHEMBL14045979 | 0.80 | KDM4E (0.50) | FASNCHEK1HRH3 | |
| SCHEMBL12489379 | 0.80 | FASN (0.47) | FASNCHEK1PANK3 | |
| SCHEMBL22047801 | 0.78 | CHEK1 (0.40) | FASNCHEK1 | |
| SCHEMBL18721893 | 0.78 | ESR2 (0.44) | FASNCHEK1PANK3HRH3 | |
| SCHEMBL3237238 | 0.76 | ESR2 (0.46) | FASNCHEK1PANK3HRH3PDE4B | |
| Hydrochloric Acid SCHEMBL12489003 | 0.76 | CHEK1 (0.49) | CHEK1TLR9TLR8TLR7 | |
| SCHEMBL3555307 | 0.75 | CHEK1 (0.33) | FASNCHEK1HRH3 | |
| SCHEMBL12049591 | 0.74 | CHEK1 (0.43) | FASNCHEK1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264737-A1 | Heterocyclic Modulators of Lipid Synthesis | 3-V BIOSCIENCES, INC. (US) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264737-A1 | Heterocyclic Modulators of Lipid Synthesis | FASN, FADS1, FADS2 | FASN 1/4885CHEK1 3125/4885PANK3 1362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.