Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774440 | 0.84 | AGTR1 (0.63) | AGTR1 | |
| SCHEMBL2777771 | 0.81 | AGTR1 (0.83) | AGTR1 | |
| SCHEMBL13475106 | 0.76 | AGTR1 (0.70) | AGTR1 | |
| SCHEMBL2775075 | 0.75 | AGTR1 (0.76) | AGTR1 | |
| SCHEMBL2773764 | 0.75 | AGTR1 (0.76) | AGTR1 | |
| SCHEMBL2774300 | 0.74 | AGTR1 (0.76) | AGTR1 | |
| SCHEMBL13070823 | 0.72 | AGTR1 (0.77) | AGTR1 | |
| SCHEMBL13311524 | 0.72 | AGTR1 (0.77) | AGTR1 | |
| SCHEMBL13475111 | 0.72 | AGTR1 (0.55) | AGTR1 | |
| SCHEMBL2776338 | 0.72 | AGTR1 (0.65) | AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151440-A1 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2010-02-10 | — | — | EP | disclosed |