Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MPL | P40238 | 2/20 | 0.46 |
| ▸ | CTRC | Q99895 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306052 | 0.89 | CYP1A2 (0.56) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL306051 | 0.89 | CYP1A2 (0.56) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL29350795 | 0.89 | CYP1A2 (0.56) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL13474931 | 0.88 | THRB (0.54) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL11699196 | 0.82 | THRB (0.59) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL11699193 | 0.82 | THRB (0.59) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL17804074 | 0.80 | THRB (0.76) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL28136394 | 0.79 | MAPT (0.68) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL11023723 | 0.78 | CYP1A2 (0.59) | THRBMAPTL3MBTL1MAPK1KDM4E | |
| SCHEMBL30124927 | 0.78 | CYP1A2 (0.59) | THRBMAPTL3MBTL1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100047426-A1 | METHOD FOR MODULATING THE TASTE OF MATERIAL COMPOSITIONS CONTAINING AT LEAST ONE HIGH INTENSITY SWEETENER (HIS) | BASF SE (DE) | 2010-02-25 | — | — | US | disclosed |