Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12271041 | 0.81 | SLC6A3 (0.33) | SLC6A4HTR2ASLC6A3 | |
| SCHEMBL16151504 | 0.81 | SLC6A3 (0.35) | SLC6A4SLC6A3 | |
| SCHEMBL2406878 | 0.76 | HTR2A (0.33) | SLC6A4HTR2ARAPGEF4 | |
| SCHEMBL2406879 | 0.71 | KDM4E (0.50) | SLC6A4SLC6A3 | |
| SCHEMBL2411602 | 0.71 | SLC6A2 (0.32) | SLC6A4SLC6A3 | |
| SCHEMBL12270807 | 0.69 | SLC6A4 (0.32) | SLC6A4HTR2AKCNH2SLC6A3RAPGEF4 | |
| SCHEMBL13476022 | 0.67 | KDM4E (0.49) | SLC6A4HTR2AKCNH2SLC6A3 | |
| SCHEMBL12271042 | 0.66 | HTR2A (0.32) | HTR2A | |
| SCHEMBL2407036 | 0.66 | SLC6A4 (0.33) | SLC6A4HTR2AKCNH2SLC6A3 | |
| SCHEMBL12273708 | 0.65 | PPARG (0.34) | SLC6A4KCNH2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018836-A2 | POLYGLUTAMINE AGGREGATION INHIBITOR | 独立行政法人科学技術振興機構 (JP) | 2010-02-18 | — | — | WO | disclosed |
| WO-2010018837-A2 | PROTEIN CROSS-LINKING INHIBITOR | 独立行政法人科学技術振興機構 (JP) | 2010-02-18 | — | — | WO | disclosed |