Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3445913 | 0.86 | BUB1 (0.60) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL1692228 | 0.78 | BUB1 (0.65) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL31471645 | 0.77 | NPC1 (0.47) | HPGDLMNAGAASMN1; SMN2CSNK2A1 | |
| SCHEMBL28762186 | 0.76 | LMNA (0.32) | LMNA | |
| SCHEMBL31471536 | 0.72 | CSNK2A1 (0.42) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL31471525 | 0.72 | CSNK2A1 (0.42) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL1266405 | 0.72 | CSNK2A1 (0.50) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL31471533 | 0.72 | CSNK2A1 (0.42) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL13397249 | 0.71 | CSNK2A1 (0.42) | HPGDLMNAGAASMN1; SMN2ELANE | |
| SCHEMBL17498062 | 0.71 | TP53 (0.39) | HPGDLMNAHTTMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010021149-A1 | SPIRO COMPOUND CAPABLE OF INHIBITING ACID SECRETION | 武田薬品工業株式会社 (JP) | 2010-02-25 | — | — | WO | disclosed |