Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | FABP7 | O15540 | 1/20 | 0.49 |
| ▸ | FABP3 | P05413 | 1/20 | 0.49 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6565732 | 0.91 | HSD17B10 (0.47) | KMT2AMEN1SMN1; SMN2LMNANPSR1 | |
| Benzene SCHEMBL7925278 | 0.86 | TDP1 (0.50) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL3302 | 0.86 | TDP1 (0.50) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL370622 | 0.86 | TDP1 (0.50) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL27902340 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL27326182 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| Ammonia Solution, Strong SCHEMBL28185209 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL10975650 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| Hydrochloric Acid SCHEMBL3896561 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 | |
| SCHEMBL11224568 | 0.84 | TDP1 (0.48) | KDM4ERAB9ATDP1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766450-A1 | SUBSTITUTED AMINO ALCOHOLS AS CHIRAL DOPANTS | FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V. (DE) | 2014-08-20 | — | — | EP | disclosed |
| WO-2013053752-A1 | SUBSTITUTED AMINO ALCOHOLS AS CHIRAL DOPANTS | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2013-04-18 | — | — | WO | disclosed |
| US-8173700-B2 | Salts of substituted allophanates and their use in drugs | GRUENENTHAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173700-B2 | Salts of substituted allophanates and their use in drugs | GRUENENTHAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8173700-B2 | Salts of substituted allophanates and their use in drugs | GRUENENTHAL GMBH (DE) | 2012-05-08 | — | — | US | disclosed |
| US-8063021-B2 | Ketolide anti-infective compounds | KOSAN BIOSCIENCES INCORPORATED (US) | 2011-11-22 | — | — | US | disclosed |
| EP-2242747-A1 | SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | Sanofi-Aventis (FR) | 2010-10-27 | — | — | EP | disclosed |
| EP-2111236-A2 | NOVEL CASCADE POLYMER COMPLEXES, METHOD FOR THEIR PRODUCTION AND PHARMACEUTICAL AGENTS CONTAINING THE SAME | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-10-28 | — | — | EP | disclosed |
| WO-2009097997-A1 | SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |
| EP-1888514-B1 | SALTS OF SUBSTITUTED ALLOPHANATES AND THEIR USE IN DRUGS | GRUENENTHAL GMBH (DE) | 2009-03-18 | — | — | EP | disclosed |
| EP-0466183-A1 | Cyclosiloxanes with mesogenic side groups | Consortium für elektrochemische Industrie GmbH (DE) | 1992-01-15 | — | — | EP | disclosed |
| EP-0368176-A1 | Esters of carboximidic acid, their preparation, and their use as pesticides | CIBA-GEIGY AG (CH) | 1990-05-16 | — | — | EP | disclosed |
| EP-0219756-A1 | Acrylic amides | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-04-29 | — | — | EP | disclosed |
| EP-0061013-B1 | PROCESS FOR THE PREPARATION OF POLYISOCYANATES | BAYER AG (DE) | 1984-06-27 | — | — | EP | disclosed |
| EP-0041043-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE | CIBA-GEIGY AG (CH) | 1983-11-09 | — | — | EP | disclosed |
| EP-0040177-B1 | PROCESS FOR THE PREPARATION OF BENZENE OR NAPHTHALENE ALKENYL CARBOXYLIC ACID DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-07-20 | — | — | EP | disclosed |
| US-4376731-A | 2-NITRILES THEREOF | BOEHRINGER MANNHEIM GMBH (DE) | 1983-03-15 | — | — | US | disclosed |
| EP-0061013-A1 | Process for the preparation of polyisocyanates | BAYER AG (DE) | 1982-09-29 | — | — | EP | disclosed |
| EP-0041043-A1 | Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | disclosed |
| EP-0040177-A1 | Process for the preparation of benzene or naphthalene alkenyl carboxylic acid derivatives | CIBA-GEIGY AG (CH) | 1981-11-18 | — | — | EP | disclosed |