SCHEMBL1347769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1941869	0.93	RXFP1 (0.56)	RXFP1LMNAPOLBMEN1KMT2A
	SCHEMBL1346946	0.90	PKM (0.44)	RXFP1LMNAMEN1KMT2AALDH1A1
	SCHEMBL1347067	0.90	MAPK14 (0.48)	RXFP1PPIALMNAPOLBMEN1
	SCHEMBL1347197	0.87	KDR (0.54)	LMNAPOLBMEN1KMT2AALDH1A1
	SCHEMBL1346852	0.83	KDR (0.55)	RXFP1PPIALMNAMEN1KMT2A
	SCHEMBL1344783	0.83	KDR (0.53)	RXFP1PPIALMNAPOLBMEN1
	SCHEMBL13604079	0.83	MAPK14 (0.46)	RXFP1PPIALMNAPOLBMEN1
	SCHEMBL1943134	0.82	KDR (0.52)	RXFP1LMNAMEN1KMT2AALDH1A1
	SCHEMBL1942982	0.82	RXFP1 (0.53)	RXFP1LMNAPOLBMEN1KMT2A
	SCHEMBL1941473	0.81	KDR (0.48)	LMNAMEN1KMT2AALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.