Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PDE5A | O76074 | 2/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11512622 | 0.91 | IDO1 (0.55) | IDO1MAPTHTTKDM4EPDE5A | |
| SCHEMBL28739378 | 0.87 | TLR8 (0.47) | MAPTHTTKDM4EPOLBL3MBTL1 | |
| SCHEMBL24846615 | 0.85 | L3MBTL1 (0.47) | MAPTHTTKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL28732241 | 0.84 | IDO1 (0.52) | IDO1MAPTHTTKDM4EPOLB | |
| SCHEMBL9011307 | 0.84 | L3MBTL1 (0.49) | MAPTHTTL3MBTL1NPSR1EPHX1 | |
| SCHEMBL3014760 | 0.81 | IDO1 (0.45) | IDO1MAPTHTTKDM4EPOLB | |
| SCHEMBL11996900 | 0.78 | MAPT (0.46) | IDO1MAPTHTTKDM4EPOLB | |
| SCHEMBL1485722 | 0.77 | MAPT (0.78) | IDO1MAPTHTTL3MBTL1ALDH1A1 | |
| SCHEMBL29449705 | 0.77 | POLB (0.60) | IDO1MAPTHTTKDM4EPOLB | |
| SCHEMBL653948 | 0.77 | POLB (0.60) | IDO1MAPTHTTKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778677-B1 | HETEROCYCLIC CONDENSED COMPOUNDS USEFUL AS ANTIDIURETIC AGENTS | VANTIA LTD (GB) | 2010-02-03 | — | — | EP | disclosed |