Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 2/20 | 0.49 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.40 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969857 | 0.92 | NPY4R (0.41) | CALCRLOPRL1KDM1AMAOAKDM1B | |
| SCHEMBL12972169 | 0.91 | CALCRL (0.52) | CALCRLSSTR3OPRK1OPRL1HRH1 | |
| SCHEMBL13043894 | 0.90 | CALCRL (0.52) | CALCRLSSTR3OPRK1OPRL1HRH1 | |
| SCHEMBL13043888 | 0.90 | CALCRL (0.44) | CALCRLSSTR3OPRK1OPRL1HRH1 | |
| SCHEMBL19456893 | 0.90 | CALCRL (0.43) | CALCRLSSTR3OPRK1OPRL1KDM1A | |
| SCHEMBL22969940 | 0.89 | OPRL1 (0.42) | CALCRLOPRL1KDM1AMAOAKDM1B | |
| SCHEMBL22910386 | 0.88 | CALCRL (0.51) | CALCRLSSTR3HRH1KDM1AMAOA | |
| SCHEMBL13477997 | 0.87 | CALCRL (0.49) | CALCRLOPRL1HRH1 | |
| SCHEMBL26825462 | 0.86 | HDAC1 (0.49) | CALCRLHDAC1 | |
| SCHEMBL22549355 | 0.85 | CALCRL (0.43) | CALCRLSSTR3OPRK1HRH1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659241-B2 | monoclonal antibody conjugated with peptide drug such as dolastatin derivative | SEATTLE GENETICS, INC. (US) | 2010-02-09 | — | — | US | disclosed |