Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.42 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 7/20 | 0.39 |
| ▸ | MAOA | P21397 | 5/20 | 0.39 |
| ▸ | RCOR1 | Q9UKL0 | 3/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22969857 | 0.97 | NPY4R (0.41) | OPRL1CALCRLKDM1AMAOARCOR1 | |
| SCHEMBL22969845 | 0.92 | TACR1 (0.39) | OPRL1CALCRLKDM1AMAOARCOR1 | |
| SCHEMBL13477993 | 0.89 | CALCRL (0.49) | OPRL1CALCRLKDM1AMAOARCOR1 | |
| SCHEMBL22970116 | 0.89 | MAP1LC3B (0.40) | OPRL1SIRT1SIRT2SIRT5 | |
| SCHEMBL22969859 | 0.89 | KDM1A (0.43) | KDM1AMAOARCOR1KDM1BSIRT1 | |
| SCHEMBL22969937 | 0.88 | OPRL1 (0.34) | OPRL1SIRT1SIRT2SIRT5 | |
| SCHEMBL18811640 | 0.87 | NPY5R (0.39) | OPRL1SIRT1SIRT2NPY1RNPY2R | |
| SCHEMBL22624856 | 0.87 | FAP (0.40) | OPRL1SIRT1SIRT2SIRT5 | |
| SCHEMBL24831925 | 0.86 | SIRT2 (0.37) | OPRL1ITGB1SIRT1SIRT2SIRT5 | |
| SCHEMBL23690548 | 0.86 | OPRL1 (0.40) | OPRL1CALCRLKDM1AMAOARCOR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021022678-A1 | ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF | 烟台迈百瑞国际生物医药股份有限公司 | 2021-02-11 | — | — | WO | disclosed |