SCHEMBL13478686

SCHEMBL13478686

CC(C)(C)[C@H]1OC[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.38
LMNA P02545 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11946933 1.00 THRB (0.38) THRBLMNA
SCHEMBL19002176 1.00 THRB (0.38) THRBLMNA
SCHEMBL14556074 1.00 THRB (0.38) THRBLMNA
SCHEMBL19829885 1.00 THRB (0.38) THRBLMNA
SCHEMBL12038672 1.00 THRB (0.38) THRBLMNA
SCHEMBL16406411 1.00 THRB (0.38) THRBLMNA
SCHEMBL17190802 1.00 THRB (0.38) THRBLMNA
SCHEMBL14556018 1.00 THRB (0.38) THRBLMNA
SCHEMBL14556014 1.00 THRB (0.38) THRBLMNA
SCHEMBL11953924 1.00 THRB (0.38) THRBLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7655646-B2 Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals THALLION PHARMACEUTICALS, INC. (CA) 2010-02-02 US disclosed