Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18068842 | 1.00 | THRB (0.37) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL18822220 | 0.87 | THRB (0.40) | THRBLMNASUCNR1 | |
| SCHEMBL18530044 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL18911637 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL5035096 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL23720424 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL12346259 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL20888679 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL21097517 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 | |
| SCHEMBL24212766 | 0.82 | SUCNR1 (0.39) | THRBLMNASUCNR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655646-B2 | Dibenzodiazepinone analogues, processes for their production and their use as pharmaceuticals | THALLION PHARMACEUTICALS, INC. (CA) | 2010-02-02 | — | — | US | disclosed |