Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CPS1 | P31327 | 8/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14337281 | 1.00 | EPHX2 (0.35) | EPHX2CPS1DHODHALDH1A1HPGD | |
| SCHEMBL2741548 | 0.90 | EPHX2 (0.42) | EPHX2DHODHALDH1A1ESR2HIF1A | |
| SCHEMBL14337423 | 0.87 | EPHX2 (0.37) | EPHX2DHODHHIF1AMMP12PDE2A | |
| SCHEMBL13480389 | 0.87 | EPHX2 (0.37) | EPHX2DHODHHIF1AMMP12PDE2A | |
| SCHEMBL13671359 | 0.86 | ESR2 (0.38) | CPS1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL14337205 | 0.86 | ESR2 (0.38) | CPS1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL10014268 | 0.83 | HIF1A (0.40) | CPS1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL13480369 | 0.82 | ESR2 (0.36) | ALDH1A1HPGDTSHRHSD17B10ESR2 | |
| SCHEMBL10091184 | 0.82 | GAA (0.43) | DHODHALDH1A1HPGDHSD17B10ESR2 | |
| SCHEMBL14337520 | 0.82 | HIF1A (0.43) | CPS1ALDH1A1HPGDTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662443-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2010-02-16 | — | — | US | disclosed |
| US-20080121843-A1 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | HECKMEIER MICHAEL | 2008-05-29 | — | — | US | disclosed |
| US-7303791-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GMBH (DE) | 2007-12-04 | — | — | US | disclosed |
| US-7303791-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GMBH (DE) | 2007-12-04 | — | — | US | disclosed |