Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CPS1 | P31327 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13671359 | 1.00 | ESR2 (0.38) | ESR2HIF1ACPS1ALDH1A1HPGD | |
| SCHEMBL10014268 | 0.89 | HIF1A (0.40) | ESR2HIF1ACPS1ALDH1A1HPGD | |
| SCHEMBL13480369 | 0.88 | ESR2 (0.36) | ESR2HIF1AALDH1A1HPGDTSHR | |
| SCHEMBL13671363 | 0.88 | HIF1A (0.43) | ESR2HIF1ACPS1ALDH1A1HPGD | |
| SCHEMBL10091184 | 0.88 | GAA (0.43) | ESR2HIF1AALDH1A1HPGDHSD17B10 | |
| SCHEMBL14337520 | 0.88 | HIF1A (0.43) | ESR2HIF1ACPS1ALDH1A1HPGD | |
| SCHEMBL12718785 | 0.87 | SLC6A3 (0.40) | ESR2HIF1ACPS1 | |
| SCHEMBL13986755 | 0.86 | CYP1A2 (0.42) | ESR2HIF1ACPS1ALDH1A1 | |
| SCHEMBL14337281 | 0.86 | EPHX2 (0.35) | ESR2HIF1ACPS1ALDH1A1HPGD | |
| SCHEMBL13480375 | 0.86 | EPHX2 (0.35) | ESR2HIF1ACPS1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7604851-B2 | Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2009-10-20 | — | — | US | disclosed |
| US-7449222-B2 | Liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-11-11 | — | — | US | disclosed |
| US-20080121843-A1 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | HECKMEIER MICHAEL | 2008-05-29 | — | — | US | disclosed |
| US-7361388-B2 | Liquid-crystalline compounds having a tetrahydropyran ring | MERCK PATENT GMBH (DE) | 2008-04-22 | — | — | US | disclosed |
| US-7361288-B2 | Components for high-frequency technology | MERCK PATENT GESELLSCHAFT MIT BESSCHRANKTER HAFTUNG (DE) | 2008-04-22 | — | — | US | disclosed |
| US-7344761-B2 | Liquid-crystalline compounds | MERCK PATENT GESELLASCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-03-18 | — | — | US | disclosed |
| US-7316830-B2 | Phenyl fluorobenzoate (p-fluorophenyl 4-(trans-4-propylcyclohexyl)-2,6-difluorobenzoate) and a bicyclohexyl compound (4,4'-vinylbicyclohexyl); very high resistivity at the same time as a broad operating temperature range, short response times, even at low temperatures, and a low threshold voltage | MERCK PATENT GMBH (DE) | 2008-01-08 | — | — | US | disclosed |
| US-7303791-B2 | Liquid crystals having a terminal polar radical and a terminal CH3 group and simultaneously having very high specific resistances and low threshold voltages requiring a high clearing point and low rotational viscosity; matrices | MERCK PATENT GMBH (DE) | 2007-12-04 | — | — | US | disclosed |
| US-20070269614-A1 | Containing at least two nitrile-free mesogenic compounds, one of which contains rings including a phenyl ring llinked by at least one -CF2O- group; electrooptical dispalys | HECKMEIER MICHAEL | 2007-11-22 | — | — | US | disclosed |
| US-7291367-B2 | Liquid-crystalline compounds | MERCK PATENT GMBH (DE) | 2007-11-06 | — | — | US | disclosed |
| US-7250198-B2 | For electrooptical display | MERCK PATENT GMBH (DE) | 2007-07-31 | — | — | US | disclosed |
| US-7189440-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2007-03-13 | — | — | US | disclosed |
| US-7179511-B2 | For use in electro-optical displays | MERCK PATENT GMBH (DE) | 2007-02-20 | — | — | US | disclosed |
| US-20070034828-A1 | Containing 3 directly connected rings: a fluorophenyl ring, a tetrahydropyran ring and either another tetrahydropyran ring or a 1,3-dioxane ring; electrooptical displays; | MERCK PATENT GMBH (DE) | 2007-02-15 | — | — | US | disclosed |