Sugi Predict

Sugi Predict / Compounds / SCHEMBL13480845

SCHEMBL13480845

SCHEMBL13480845

CC12C=CC(C)(O1)[C@H]1C(=O)N(c3cccc(C(F)(F)F)c3)C(=O)[C@H]12

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CACNA1B Q00975 7/20 0.66
▸ APBA1 Q02410 7/20 0.66
▸ AR P10275 1/20 0.59
▸ MEN1 O00255 3/20 0.49
▸ KMT2A Q03164 3/20 0.49
▸ ALDH1A1 P00352 5/20 0.48
▸ TP53 P04637 2/20 0.45
▸ HPGD P15428 2/20 0.45
▸ MAPK1 P28482 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ NPSR1 Q6W5P4 2/20 0.45
▸ HSD17B10 Q99714 2/20 0.45
▸ MAPT P10636 1/20 0.45
▸ LMNA P02545 1/20 0.45
▸ RAB9A P51151 1/20 0.45
▸ ATM Q13315 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ TSHR P16473 1/20 0.44
▸ CYP2C8 P10632 1/20 0.42
▸ CYP2C9 P11712 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3174063 1.00 CACNA1B (0.66) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL14103265 1.00 CACNA1B (0.66) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL4701653 1.00 CACNA1B (0.66) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL3174073 1.00 CACNA1B (0.66) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL3181970 0.85 AR (0.52) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL3181956 0.85 AR (0.52) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL13870655 0.85 AR (0.52) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL13480910 0.85 AR (0.52) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL5238405 0.85 AR (0.52) CACNA1BAPBA1ARMEN1KMT2A
SCHEMBL13480846 0.82 AR (0.49) CACNA1BAPBA1ARMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7655689-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-02 — — US disclosed
US-7655689-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2010-02-02 — — US disclosed
US-7517904-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2009-04-14 — — US disclosed
US-7517904-B2 Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2009-04-14 — — US disclosed
US-7470797-B2 Fused heterocyclic imido and amido compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2008-12-30 — — US disclosed
US-7470797-B2 Fused heterocyclic imido and amido compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2008-12-30 — — US disclosed
US-7342034-B2 Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2008-03-11 — — US disclosed
US-7342034-B2 Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2008-03-11 — — US disclosed
US-7291637-B2 Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2007-11-06 — — US disclosed
US-7291637-B2 Fused heterocyclic compounds and analogs thereof, modulators of nuclear hormone receptor function BRISTOL-MYERS SQUIBB COMPANY (US) 2007-11-06 — — US disclosed
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