Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.45 |
| ▸ | APBA1 | Q02410 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14103265 | 0.82 | CACNA1B (0.66) | ARMEN1KMT2AALDH1A1CACNA1B | |
| SCHEMBL4701653 | 0.82 | CACNA1B (0.66) | ARMEN1KMT2AALDH1A1CACNA1B | |
| SCHEMBL3174063 | 0.82 | CACNA1B (0.66) | ARMEN1KMT2AALDH1A1CACNA1B | |
| SCHEMBL3174073 | 0.82 | CACNA1B (0.66) | ARMEN1KMT2AALDH1A1CACNA1B | |
| SCHEMBL13480845 | 0.82 | CACNA1B (0.66) | ARMEN1KMT2AALDH1A1CACNA1B | |
| SCHEMBL4089587 | 0.81 | PTPN1 (0.43) | MEN1KMT2APTPN1ALDH1A1HPGD | |
| SCHEMBL13480773 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CACNA1BAPBA1 | |
| SCHEMBL3194347 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CACNA1BAPBA1 | |
| SCHEMBL3194360 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CACNA1BAPBA1 | |
| SCHEMBL3194353 | 0.79 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1CACNA1BAPBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |
| US-7655689-B2 | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function | BRISTOL-MYERS SQUIBB COMPANY (US) | 2010-02-02 | — | — | US | disclosed |