Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 5/20 | 0.53 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.53 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 3/20 | 0.39 |
| ▸ | LAP3 | P28838 | 4/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | XPNPEP1 | Q9NQW7 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13481579 | 1.00 | ANPEP (0.53) | ANPEPDNPEPSLC7A5KISS1RSLC1A3 | |
| SCHEMBL13481795 | 1.00 | ANPEP (0.53) | ANPEPDNPEPSLC7A5KISS1RSLC1A3 | |
| SCHEMBL13481580 | 1.00 | ANPEP (0.53) | ANPEPDNPEPSLC7A5KISS1RSLC1A3 | |
| SCHEMBL2031045 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL11467290 | 0.81 | ANPEP (0.53) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL2034368 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL762515 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL2029393 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL1247473 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 | |
| SCHEMBL2452941 | 0.81 | SLC7A5 (0.56) | ANPEPDNPEPSLC7A5SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666391-B2 | Therapeutic treating breast cancer | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2010-02-23 | — | — | US | disclosed |