Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22993962 | 0.94 | CRBN (0.30) | — | |
| SCHEMBL18746123 | 0.79 | NEK2 (0.37) | — | |
| SCHEMBL20206747 | 0.71 | CRBN (0.33) | — | |
| SCHEMBL3186446 | 0.71 | CCR2 (0.32) | CCR2 | |
| SCHEMBL10427670 | 0.70 | CCR2 (0.35) | CCR2 | |
| SCHEMBL14626896 | 0.69 | — | — | |
| SCHEMBL22978935 | 0.68 | — | — | |
| SCHEMBL22978934 | 0.68 | — | — | |
| SCHEMBL22993753 | 0.68 | PIK3CD (0.39) | — | |
| SCHEMBL3193996 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41149-E1 | Stereoisomerically pure 7-[(7S)-7-amino-5-azaspiro[2.4]heptan-5-yl]-6-fluoro-1-[(1R,2S)-2-fluoro-1-cyclopropyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid or a pharmaceutically acceptable salt thereof; antibacterial agents | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2010-02-23 | — | — | US | disclosed |