Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27404 | 0.91 | PTGES2 (0.60) | PTGES2GAAL3MBTL1POLBLMNA | |
| SCHEMBL12032406 | 0.85 | PTGES2 (0.56) | PTGES2GAAL3MBTL1LMNAHTT | |
| SCHEMBL13484276 | 0.80 | PFKFB3 (0.59) | GAAPOLBLMNAHTTALDH1A1 | |
| SCHEMBL3472410 | 0.78 | PTGES2 (0.64) | PTGES2GAAL3MBTL1POLBRXFP1 | |
| SCHEMBL3473539 | 0.77 | PTGES2 (0.65) | PTGES2GAAL3MBTL1POLBRXFP1 | |
| SCHEMBL3473288 | 0.77 | GAA (0.64) | PTGES2GAAL3MBTL1POLBHTT | |
| SCHEMBL3472654 | 0.76 | PTGES2 (0.64) | PTGES2GAAL3MBTL1POLBRXFP1 | |
| SCHEMBL13011943 | 0.76 | PTGES2 (1.00) | PTGES2GAAL3MBTL1POLBRXFP1 | |
| SCHEMBL15480577 | 0.75 | GAA (0.63) | PTGES2GAAL3MBTL1POLBLMNA | |
| SCHEMBL3475279 | 0.75 | PTGES2 (0.60) | PTGES2GAAL3MBTL1POLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7659272-B2 | CCR9 inhibitors and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2010-02-09 | — | — | US | disclosed |