Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM5C | P41229 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13558758 | 0.84 | MEN1 (0.40) | HSD17B10TDP1ADRA1ALMNAEPHX2 | |
| SCHEMBL22735084 | 0.83 | ECE1 (0.42) | ECE1ADRA1APLA2G2ALMNASLC15A2 | |
| SCHEMBL12295177 | 0.82 | TDP1 (0.38) | ECE1HSD17B10TDP1 | |
| SCHEMBL13035367 | 0.81 | HSD17B10 (0.31) | HSD17B10TDP1 | |
| SCHEMBL12363095 | 0.79 | HSD17B10 (0.42) | HSD17B10TDP1 | |
| SCHEMBL22281707 | 0.79 | TDP1 (0.42) | HSD17B10TDP1 | |
| SCHEMBL3696695 | 0.79 | EGLN1 (0.43) | ECE1HSD17B10TDP1PLA2G2ALMNA | |
| SCHEMBL11985010 | 0.78 | HSD17B10 (0.34) | HSD17B10TDP1 | |
| SCHEMBL12012184 | 0.78 | HSD17B10 (0.41) | HSD17B10TDP1TSHR | |
| SCHEMBL205904 | 0.76 | EPHX1 (0.50) | ECE1TDP1ADRA1APLA2G2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8337941-B2 | Fluorescent substrates for monoamine transporters as optical false neurotransmitters | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100035279-A1 | Fluorescent Substrates for Monoamine Transporters as Optical False Neurotransmitters | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-11 | — | — | US | disclosed |
| US-20080113573-A1 | Partially fluorinated amino acid derivatives as gelling and surface active agents | E. I. DU PONT DE NEMOURS AND COMPANY | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035279-A1 | Fluorescent Substrates for Monoamine Transporters as Optical False Neurotransmitters | SLC18A2, SLC6A2, SLC18A3 | ECE1 1282/4885HSD17B10 1042/4885TDP1 2026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.