Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12363095 | 0.83 | HSD17B10 (0.42) | TDP1HSD17B10CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL12012184 | 0.81 | HSD17B10 (0.41) | TDP1HSD17B10ACHEALDH1A1MEN1 | |
| SCHEMBL13484350 | 0.79 | ECE1 (0.39) | TDP1HSD17B10 | |
| SCHEMBL12093782 | 0.79 | ACHE (0.57) | ACHEGAAEPHX1 | |
| SCHEMBL16682368 | 0.78 | TDP1 (0.38) | TDP1HSD17B10ALDH1A1MEN1KMT2A | |
| SCHEMBL12295177 | 0.78 | TDP1 (0.38) | TDP1HSD17B10 | |
| SCHEMBL22281700 | 0.78 | DNM1 (0.40) | TDP1HSD17B10SMN1; SMN2ALDH1A1USP2 | |
| SCHEMBL824789 | 0.77 | — | — | |
| SCHEMBL3696695 | 0.74 | EGLN1 (0.43) | TDP1HSD17B10SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL499171 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020154447-A1 | MTORC MODULATORS AND USES THEREOF | AEOVIAN PHARMACEUTICALS, INC. (US) | 2020-07-30 | — | — | WO | disclosed |