Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744530 | 0.80 | — | — | |
| SCHEMBL11445494 | 0.74 | — | — | |
| SCHEMBL2600750 | 0.73 | SMN1; SMN2 (0.36) | SMN1; SMN2 | |
| SCHEMBL7350740 | 0.70 | — | — | |
| SCHEMBL7350745 | 0.70 | — | — | |
| SCHEMBL5565094 | 0.67 | — | — | |
| SCHEMBL26247534 | 0.67 | KDM4E (0.35) | KDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL11455599 | 0.65 | — | — | |
| SCHEMBL13566377 | 0.64 | — | — | |
| SCHEMBL10193024 | 0.64 | MAPT (0.33) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7662971-B2 | enzyme inhibitor for treating sleep disorders | THE SCRIPPS RESEARCH INSTITUTE (US) | 2010-02-16 | — | — | US | disclosed |