Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.71 |
| ▸ | PLA2G1B | P04054 | 9/20 | 0.71 |
| ▸ | PLA2G10 | O15496 | 5/20 | 0.71 |
| ▸ | PLA2G5 | P39877 | 4/20 | 0.71 |
| ▸ | PLA2G2E | Q9NZK7 | 4/20 | 0.71 |
| ▸ | PLA2G2F | Q9BZM2 | 2/20 | 0.58 |
| ▸ | PLA2G2D | Q9UNK4 | 2/20 | 0.58 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.58 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.58 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.58 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.58 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485005 | 0.95 | PLA2G2A (0.69) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13484831 | 0.95 | PLA2G2A (0.78) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13484878 | 0.95 | PLA2G2A (0.78) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13485008 | 0.91 | PLA2G2A (0.67) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13484882 | 0.90 | PLA2G2A (0.75) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13485002 | 0.87 | PLA2G2A (0.60) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13485004 | 0.87 | PLA2G2A (0.67) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13484838 | 0.87 | PLA2G2A (0.72) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13484880 | 0.86 | PLA2G2A (0.73) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E | |
| SCHEMBL13485000 | 0.85 | PLA2G2A (0.69) | PLA2G2APLA2G1BPLA2G10PLA2G5PLA2G2E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7666898-B2 | Multivalent indole compounds and use thereof as phospholipase-A2 inhibitors | ILYPSA, INC. (US) | 2010-02-23 | — | — | US | disclosed |