Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485176 | 1.00 | TDP1 (0.47) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9308341 | 0.87 | MAPK1 (0.53) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9308336 | 0.87 | MAPK1 (0.53) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9308347 | 0.87 | MAPK1 (0.53) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11650083 | 0.85 | MAPT (0.56) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL11650087 | 0.85 | MAPT (0.56) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL12307313 | 0.83 | NPC1 (0.57) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL15682381 | 0.83 | NPC1 (0.57) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL18407153 | 0.81 | EGFR (0.49) | TDP1MAPK1ALDH1A1TSHRHSD17B10 | |
| SCHEMBL269293 | 0.79 | ALDH1A1 (0.73) | TDP1MAPK1ALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100031453-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT | L'OREAL S.A. (FR) | 2010-02-11 | — | — | US | disclosed |
| US-20100031453-A1 | COMPOSITION FOR DYEING KERATIN FIBRES, COMPRISING A CATIONIC DIAZO DIRECT DYE CONTAINING A 2-IMIDAZOLIUM UNIT | L'OREAL S.A. (FR) | 2010-02-11 | — | — | US | disclosed |