Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14253082 | 0.95 | THRB (0.41) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL160932 | 0.95 | THRB (0.46) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL15254107 | 0.87 | THRB (0.41) | THRBMEN1POLBKMT2A | |
| SCHEMBL111075 | 0.87 | THRB (0.41) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL12250337 | 0.87 | THRB (0.41) | THRBMEN1POLBKMT2A | |
| SCHEMBL20435059 | 0.87 | THRB (0.41) | THRBMEN1POLBKMT2A | |
| SCHEMBL38755 | 0.87 | THRB (0.41) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL10821996 | 0.85 | THRB (0.40) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL7788195 | 0.85 | THRB (0.40) | THRBMEN1POLBKMT2ACA1 | |
| SCHEMBL12858519 | 0.85 | THRB (0.43) | THRBMEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2022812-B1 | POLYETHER-MODIFIED ORGANOPOLYSILOXANE, DIORGANOPOLYSILOXANE-POLYETHER BLOCK COPOLYMER, THEIR PRODUCTION METHODS, AND COSMETIC PREPARATION | DOW CORNING TORAY CO LTD (JP) | 2014-04-23 | — | — | EP | disclosed |
| US-8034891-B2 | Polyether-modified organopolysiloxane, diorganopolysiloxane-polyether block copolymer, their production methods, and cosmetic preparation | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-10-11 | — | — | US | disclosed |
| US-7989581-B2 | Polyether from ring-opening of glycidyl ether with (C2-C5 alkylene oxide) monohydric alcohol | DOW CORNING TORAY COMPANY, LTD. (JP) | 2011-08-02 | — | — | US | disclosed |
| US-20100036062-A1 | Polyether-Modified Organopolysiloxane, Diorganopolysiloxane-Polyether Block Copolymer, Their Production Methods, and Cosmetic Preparation | DOW TORAY CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
| US-20100022732-A1 | Polyether And Method For Producing The Same | DOW CORNING TORAY COMPANY, LTD. (JP) | 2010-01-28 | — | — | US | disclosed |