Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | AR | P10275 | 6/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207733 | 0.90 | AR (0.53) | ALDH1A1MEN1KMT2AMAPTACHE | |
| Water SCHEMBL27993079 | 0.88 | AR (0.52) | ALDH1A1MEN1KMT2AMAPTACHE | |
| SCHEMBL10937122 | 0.83 | AKR1C3 (0.52) | ALDH1A1MEN1KMT2AMAPTAR | |
| SCHEMBL9298850 | 0.82 | PTPRC (0.51) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL4050751 | 0.82 | MAPT (0.47) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL30369258 | 0.81 | POLB (0.65) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10939165 | 0.81 | AR (0.47) | ALDH1A1ARAKR1C3AKR1C2PDE7A | |
| SCHEMBL10938779 | 0.81 | POLB (0.65) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10030392 | 0.80 | GLA (0.54) | TSHRARAKR1C3AKR1C2CYP1A2 | |
| SCHEMBL28283181 | 0.80 | AKR1C3 (0.63) | ALDH1A1ARAKR1C3AKR1C2PDE7A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100036167-A1 | PROCESS FOR PRODUCTION OF 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | TORAY FINE CHEMICALS CO., LTD. (JP) | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036167-A1 | PROCESS FOR PRODUCTION OF 2,2'-BIS(TRIFLUOROMETHYL)-4,4'-DIAMINOBIPHENYL | DDT, DBF4, CYP4B1 | ALDH1A1 701/4885MEN1 4169/4885KMT2A 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.