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Sugi Predict / Targets / DBF4

DBF4

Protein DBF4 homolog A · Q9UBU7 · DBF4 on Sugi Atlas →

21,066 patent compounds predicted against DBF4, 10,172 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL612385 SCHEMBL612385 1.00 20/20
SCHEMBL613115 SCHEMBL613115 1.00 20/20
SCHEMBL613116 SCHEMBL613116 1.00 20/20
SCHEMBL614668 SCHEMBL614668 0.80 20/20
SCHEMBL612257 SCHEMBL612257 0.77 20/20
SCHEMBL614176 SCHEMBL614176 0.77 20/20
SCHEMBL614271 SCHEMBL614271 0.74 20/20
SCHEMBL611795 SCHEMBL611795 0.70 20/20
SCHEMBL614681 SCHEMBL614681 0.70 20/20
SCHEMBL612624 SCHEMBL612624 0.69 20/20
SCHEMBL613472 SCHEMBL613472 0.68 20/20
SCHEMBL611130 SCHEMBL611130 0.66 20/20
SCHEMBL614193 SCHEMBL614193 0.66 20/20
SCHEMBL614270 SCHEMBL614270 0.66 20/20
SCHEMBL613307 SCHEMBL613307 0.64 20/20
SCHEMBL614194 SCHEMBL614194 0.62 20/20
SCHEMBL612015 SCHEMBL612015 1.00 19/20
SCHEMBL613653 SCHEMBL613653 1.00 19/20
SCHEMBL613654 SCHEMBL613654 1.00 19/20
SCHEMBL613695 SCHEMBL613695 1.00 19/20

Clinical trials — most relevant to DBF4 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Combination Chemotherapy With or Without Radiation Therapy in Treating Young Patients With Newly Diagnosed Stage III or Stage IV Wilms' Tumor PHASE3COMPLETED
Reverse Transcriptase Inhibitors in AGS PHASE2COMPLETED
Mobilization and Collection of Peripheral Blood Stem Cells in Patients With Fanconi Anemia Using G-CSF and AMD3100 PHASE1/PHASE2COMPLETED
Pharmacogenetics of Disulfiram for Cocaine PHASE2COMPLETED
Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load PHASE1COMPLETED
Clinical Genetics Branch Eligibility Screening Survey nanNOT_YET_RECRUITING
Study of Individuals and Families With Aberrations in DDX41 or Similar Cancer Predisposition Variants nanRECRUITING
Diamond Blackfan Anemia Registry (DBAR) nanRECRUITING
Prevalence of a Non-Expressing 11B Mutation in Aka Peoples of the Central African Republic nanCOMPLETED
PCD New Gene Discovery nanCOMPLETED
MiRNA223 and HMGB1 as Apredictos for Drug Resistant Epilepsy nanUNKNOWN
Mutations and Phenotypes of Unclassifiable Inherited Bone Marrow Failure Syndromes nanRECRUITING
Evaluation of Formin Gene Status and Expression in Myeloproliferative and Myelodysplastic Disorders nanCOMPLETED
Effect of Adenovirus E1A Oncogene on DNA Replication Dynamics nanUNKNOWN
Better Delineation of DDX3X Related Phenotype and Epigenetic Signature. nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Genetic Analysis of Hereditary Disorders of Hearing and Balance nanCOMPLETED
Exome Analysis in Hearing Impaired Patients nanUNKNOWN
DNA Damage & Repair Proteins In Patients With Atherosclerotic Coronary Artery Disease nanCOMPLETED
DICER1-related Pleuropulmonary Blastoma Cancer Predisposition Syndrome: A Natural History Study nanRECRUITING
Clinical-immunological Features of DNER Ataxia nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Shwachman Diamond Syndrome Registry and Study nanRECRUITING
Identification of a New Gene Involved in Hereditary Lipodystrophy nanCOMPLETED
Whole-genome Sequencing Study in Patients With Diminished Ovarian Reserve nanUNKNOWN
Biomarkers in SCOTland CardiomyopatHy Registry (Bio-SCOTCH) nanRECRUITING
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia nanUNKNOWN
Depressed AIRE Gene Expression Causes Immune Cell Dysfunction & Autoimmunity in Down Syndrome nanCOMPLETED
Idiopathic Dilated Cardiomyopathy nanCOMPLETED
Artificial Intelligence for the Prioritization of Genetic Background in Brugada Syndrome nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a DBF4 binder may also engage these)

ProteinNameSimilarity
Q99MU0 — 0.995 Q99MU0 →
Q9QZ41 — 0.993 Q9QZ41 →
Q7ZZH7 — 0.986 Q7ZZH7 →
Q28FY7 — 0.985 Q28FY7 →
Q9NWN3 — 0.984 Q9NWN3 →
P61594 — 0.984 P61594 →
P61591 — 0.983 P61591 →
P61593 — 0.982 P61593 →
Q96RL1 — 0.982 Q96RL1 →
Q8NEM0 — 0.981 Q8NEM0 →
A0P8Z5 — 0.981 A0P8Z5 →
Q5U5Q9 — 0.980 Q5U5Q9 →
Q7TT79 — 0.980 Q7TT79 →
P61592 — 0.980 P61592 →
Q99708 — 0.979 Q99708 →
Q86VV4 — 0.979 Q86VV4 →
Q5IFK1 — 0.978 Q5IFK1 →
Q96T21 — 0.978 Q96T21 →
Q9UHC1 — 0.978 Q9UHC1 →
Q7Z4H7 — 0.977 Q7Z4H7 →
TANK TRAF family member-associated NF-kappa-B activator 0.977 landscape →
Q8NAT2 — 0.977 Q8NAT2 →
Q9HBJ7 — 0.977 Q9HBJ7 →
A0JM80 — 0.977 A0JM80 →
Q80YR6 — 0.977 Q80YR6 →
A7MBJ2 — 0.977 A7MBJ2 →
Q6GNV6 — 0.977 Q6GNV6 →
Q5PQK4 — 0.976 Q5PQK4 →
C18orf63 Uncharacterized protein C18orf63 0.976 landscape →
Q5VXU9 — 0.976 Q5VXU9 →