SCHEMBL13487665

SCHEMBL13487665

CC1(C)c2ccccc2-c2cc(-c3c4ccccc4c(-c4cncnc4)c4ccc(-c5ccc6ccccc6c5)cc34)ccc21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 6/20 0.36
CYP11B1 P15538 5/20 0.36
CYP17A1 P05093 2/20 0.36
CYP19A1 P11511 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MAPK9 P45984 1/20 0.34
MAPK10 P53779 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2B6 P20813 1/20 0.33
CYP2C19 P33261 1/20 0.33
DHFR P00374 1/20 0.32
PDK2 Q15119 2/20 0.31
ERN1 O75460 1/20 0.31
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
PTGER3 P43115 2/20 0.31
IKBKB O14920 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13488054 0.94 CYP11B1 (0.36) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL13487797 0.90 PDK2 (0.36) PDK2
SCHEMBL13487518 0.90 ATM (0.36) CYP1A2CYP3A4PDK2
SCHEMBL13487655 0.89 CYP11B2 (0.49) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL13487604 0.89 PDK2 (0.33) CYP11B2CYP11B1KDM4ECYP1A2CYP3A4
SCHEMBL13487283 0.88 PDK2 (0.37) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL13487664 0.88 KDM4E (0.35) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E
SCHEMBL13487656 0.88 MAPK9 (0.37) CYP11B2CYP11B1CYP17A1CYP19A1MAPK9
SCHEMBL13488131 0.86 PDK2 (0.38) PDK2
SCHEMBL13487662 0.86 SIRT2 (0.33) CYP11B2CYP11B1CYP17A1CYP19A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100045170-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 CYP11B2 548/4885CYP11B1 492/4885CYP17A1 911/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.