⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5029470 | 0.97 | — | — | |
| Butane SCHEMBL4150351 | 0.89 | HSD17B10 (0.31) | — | |
| SCHEMBL297052 | 0.78 | — | — | |
| SCHEMBL333601 | 0.78 | — | — | |
| SCHEMBL3362081 | 0.78 | ALDH1A1 (0.31) | — | |
| SCHEMBL28642987 | 0.77 | — | — | |
| SCHEMBL10453087 | 0.77 | — | — | |
| SCHEMBL28686149 | 0.77 | — | — | |
| SCHEMBL7934332 | 0.75 | — | — | |
| SCHEMBL28150432 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115298192-A | 4' -O-methylene phosphonate nucleic acids and analogs thereof | 迪克纳制药公司 | 2022-11-04 | — | — | CN | disclosed |
| US-10071110-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-11 | — | — | US | disclosed |
| WO-2018156879-A1 | TREATMENT OF ADENOVIRUS WITH BRINCIDOFOVIR | CHIMERIX, INC. (US) | 2018-08-30 | — | — | WO | disclosed |
| EP-2143331-B1 | Fan type chemicals diffusing apparatus | FUMAKILLA LTD (JP) | 2018-06-20 | — | — | EP | disclosed |
| US-20170239279-A1 | PHOSPHONATE COMPOUNDS | UNIV CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9649321-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-20160303147-A1 | METHODS OF REDUCING NEPHROTOXICITY IN SUBJECTS ADMINISTERED WITH NUCLEOSIDE PHOSPHONATES | CHIMERIX, INC. | 2016-10-20 | — | — | US | disclosed |
| EP-2155257-B1 | METHODS OF REDUCING NEPHROTOXICITY IN SUBJECTS ADMINISTERED WITH NUCLEOSIDE | CHIMERIX INC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-20160067268-A1 | PHOSPHONATE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-10 | — | — | US | disclosed |
| US-9206208-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-08 | — | — | US | disclosed |
| US-20040127735-A1 | New phosphonate ester derivatives of drugs such as antivirals cidofovir, adefovir, tenofovir, azidothymidine (AZT), or bisphosphonates such as alendronate, or anticancers such as cytosine arabinoside; side effect reduction, less toxic; antiviral | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-07-01 | — | — | US | disclosed |
| US-6716825-B2 | OSTEOPOROSIS AND OTHER DISORDERS OF BONE METABOLISUM, CANCER, VIRAL INFECTIONS, AND THE LIKE. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-04-06 | — | — | US | disclosed |
| US-20040019232-A1 | Analogs of phosphonate and bisphosphonate compounds based on bone resorption suppressors (alendronic acid), viricides (cidofovir) and antineoplastic agents (bemcitabine); nontoxic; bioavailability; side effects reduction | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-01-29 | — | — | US | disclosed |
| EP-1356728-A1 | FAN TYPE CHEMICAL DISPERSION EQUIPMENT | Fumakilla Limited (JP) | 2003-10-29 | — | — | EP | disclosed |
| EP-1233770-A4 | PHOSPHONATE COMPOUNDS | UNIV CALIFORNIA AT SAN DIEGO (US) | 2003-04-16 | — | — | EP | disclosed |
| EP-1262100-A1 | FAN TYPE CHEMICALS DIFFUSING DEVICE | Fumakilla Limited (JP) | 2002-12-04 | — | — | EP | disclosed |
| EP-1233770-A2 | PHOSPHONATE COMPOUNDS | The Regents of The University of California at San Diego (US) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001039724-A2 | PHOSPHONATE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2001-06-07 | — | — | WO | disclosed |
| US-4470841-A | Certain herbicidal phosphonates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-09-11 | — | — | US | disclosed |
| EP-0073040-A2 | Organic phosphorus compounds, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-03-02 | — | — | EP | disclosed |