Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | MDM4 | O15151 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17285759 | 0.94 | TLR2 (0.49) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL11885249 | 0.91 | TLR2 (0.58) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL12787770 | 0.91 | TLR2 (0.58) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL13658468 | 0.91 | KMT2A (0.56) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL29400679 | 0.91 | KMT2A (0.56) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL17826082 | 0.91 | KMT2A (0.56) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL12928621 | 0.91 | KMT2A (0.56) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL14417866 | 0.90 | TLR2 (0.52) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL23421255 | 0.89 | KMT2A (0.50) | TLR2MDM4TP53CASP3KMT2A | |
| SCHEMBL29682496 | 0.89 | KMT2A (0.50) | TLR2MDM4TP53CASP3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048921-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | GOERNE HERBERT | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048921-A1 | PHARMACEUTICALLY ACTIVE COMPOUNDS | F11, PEPD, F13B | TLR2 3910/4885MDM4 3727/4885TP53 678/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.