Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 14/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12037701 | 1.00 | IRAK4 (0.53) | IRAK4KMT2AALDH1A1HSD17B10TP53 | |
| SCHEMBL12037704 | 0.91 | IRAK4 (0.54) | IRAK4CYP3A4 | |
| SCHEMBL12037685 | 0.89 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL12036743 | 0.87 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL17119855 | 0.87 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL12037675 | 0.86 | IRAK4 (0.72) | IRAK4 | |
| SCHEMBL12037688 | 0.86 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL12037703 | 0.80 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL12057900 | 0.80 | IRAK4 (0.70) | IRAK4 | |
| SCHEMBL12057677 | 0.79 | IRAK4 (0.48) | IRAK4KMT2AALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |