Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 20/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12036743 | 1.00 | IRAK4 (0.55) | IRAK4 | |
| SCHEMBL12037685 | 0.91 | IRAK4 (0.57) | IRAK4 | |
| SCHEMBL12037688 | 0.87 | IRAK4 (0.71) | IRAK4 | |
| SCHEMBL13493378 | 0.87 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL12037701 | 0.87 | IRAK4 (0.53) | IRAK4 | |
| SCHEMBL12036742 | 0.86 | IRAK4 (0.74) | IRAK4 | |
| SCHEMBL12037704 | 0.84 | IRAK4 (0.54) | IRAK4 | |
| SCHEMBL12037682 | 0.80 | IRAK4 (0.48) | IRAK4 | |
| SCHEMBL12037713 | 0.80 | IRAK4 (0.74) | IRAK4 | |
| SCHEMBL12057759 | 0.79 | IRAK4 (0.49) | IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2536410-B1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | MERCK SHARP & DOHME (US) | 2015-09-23 | — | — | EP | disclosed |