Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 4/20 | 0.33 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12037618 | 0.82 | IRAK4 (0.80) | IRAK4 | |
| SCHEMBL12058082 | 0.80 | IRAK4 (0.46) | IRAK4RAB9AKDM4EALDH1A1MAPT | |
| SCHEMBL13493543 | 0.79 | IRAK4 (0.37) | IRAK4 | |
| SCHEMBL13493415 | 0.79 | IRAK4 (0.58) | IRAK4RAB9ABCHEFASNNPC1 | |
| SCHEMBL12058362 | 0.77 | IRAK4 (0.41) | IRAK4 | |
| SCHEMBL13493580 | 0.76 | IRAK4 (0.38) | IRAK4 | |
| SCHEMBL12058479 | 0.76 | IRAK4 (0.39) | IRAK4 | |
| SCHEMBL13493672 | 0.75 | IRAK4 (0.37) | IRAK4 | |
| SCHEMBL12058376 | 0.75 | IRAK4 (0.42) | IRAK4KDM4EALDH1A1 | |
| SCHEMBL13493720 | 0.75 | IRAK4 (0.50) | IRAK4RAB9ANPC1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010022121-A1 | SUBSTITUTED PYRIDINE AND PYRIMIDINE DERIVATIVES AND THEIR USE IN TREATING VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2010-02-25 | — | — | WO | disclosed |