Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248840 | 0.92 | CHRM4 (0.61) | CHRM4CYP2C19CHRM2CHRM5CHRM1 | |
| SCHEMBL13494376 | 0.86 | CHRM4 (0.51) | CHRM4CYP2C19CHRM2CHRM5CHRM1 | |
| SCHEMBL1575429 | 0.80 | CHRM4 (0.49) | CHRM4CYP2C19NPC1RAB9ADRD2 | |
| SCHEMBL17117224 | 0.77 | CHRM4 (0.67) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL13494374 | 0.77 | CYP2C19 (0.46) | CHRM4CYP2C19CHRM2CHRM5CHRM1 | |
| SCHEMBL6167382 | 0.76 | MEN1 (0.46) | MEN1KMT2ANAMPT | |
| SCHEMBL596585 | 0.75 | POLB (0.48) | CHRM4MEN1CYP2C9KMT2ANAMPT | |
| SCHEMBL4029855 | 0.75 | PRMT5 (0.58) | CHRM4KMT2ANPC1RAB9AHSD11B1 | |
| SCHEMBL1193794 | 0.74 | CHRM4 (0.57) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL19187793 | 0.74 | NPC1 (0.53) | MEN1KMT2ACCR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017060-A1 | UREA DERIVATIVES AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |