Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 4/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 2/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248840 | 0.89 | CHRM4 (0.61) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL13494375 | 0.86 | CHRM4 (0.54) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL13494294 | 0.84 | CHRM4 (0.48) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL1575429 | 0.77 | CHRM4 (0.49) | CHRM4CYP2C19DRD2 | |
| SCHEMBL12378663 | 0.77 | ADAMTS5 (0.56) | — | |
| SCHEMBL12279687 | 0.76 | — | — | |
| SCHEMBL17117224 | 0.75 | CHRM4 (0.67) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL13494374 | 0.74 | CYP2C19 (0.46) | CHRM4CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL12319790 | 0.74 | DRD2 (0.55) | MEN1KMT2ADRD2DRD3 | |
| SCHEMBL12280154 | 0.73 | NAMPT (0.43) | KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010017060-A1 | UREA DERIVATIVES AS ANTIBACTERIAL AGENTS | SCHERING CORPORATION (US) | 2010-02-11 | — | — | WO | disclosed |